4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid
4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid
CAS: 669713-98-8
Molecular Formula: C16H17NO4
4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid - Names and Identifiers
| Name | 4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid |
| Synonyms | 4-(2'-N-Boc-Pyrrole)benzoicacid 4-(1-(TERT-BUTOXYCARBONYL)-1H-PYRROL-2-YL)BENZOIC ACID 4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid 4-[1-(tert-Butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid 4-[1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrol-2-yl]benzoic acid 2-(4-Carboxyphenyl)-1H-pyrrole-1-carboxylic acid 1-(1,1-dimethylethyl) ester 1H-Pyrrole-1-carboxylic acid, 2-(4-carboxyphenyl)-, 1-(1,1-dimethylethyl) ester |
| CAS | 669713-98-8 |
| InChI | InChI=1/C16H17NO4/c1-16(2,3)21-15(20)17-10-4-5-13(17)11-6-8-12(9-7-11)14(18)19/h4-10H,1-3H3,(H,18,19) |
4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid - Physico-chemical Properties
| Molecular Formula | C16H17NO4 |
| Molar Mass | 287.31 |
| Density | 1.17±0.1 g/cm3(Predicted) |
| Boling Point | 454.3±47.0 °C(Predicted) |
| Flash Point | 228.5°C |
| Vapor Presure | 4.83E-09mmHg at 25°C |
| pKa | 4.21±0.10(Predicted) |
| Refractive Index | 1.558 |
4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid - Introduction
4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid is an organic compound whose chemical structure is a substitution of benzoic acid with a 2 '-N-Boc-pyrrole group. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: White or white-like solid
-Melting point: about 131-133°C
-Molecular formula: C16H17NO4
-Molecular weight: 295.31g/mol
Use:
- 4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid can be used as an organic synthesis intermediate.
-It can be used to synthesize biologically active compounds, such as drugs, dyes and other organic family compounds.
Preparation Method: The preparation of
- 4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid is generally carried out by the following steps:
1. Add 2 '-N-Boc-pyrrole to benzoic acid under appropriate reaction conditions.
2. the reaction product is crystallized or purified to obtain 4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid.
Safety Information:
- 4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl] The specific safety of benzoic acid also needs to be evaluated according to its use conditions and actual conditions.
-Always follow laboratory safety practices and use appropriate personal protective equipment (e. g., gloves, lab clothes, and goggles) during handling and storage.
-The compound may be irritating to the eyes, skin and respiratory tract, so be careful to avoid contact with these areas.
-In case of accidental exposure or inhalation, flush the affected area immediately with plenty of water and seek medical assistance.
Nature:
-Appearance: White or white-like solid
-Melting point: about 131-133°C
-Molecular formula: C16H17NO4
-Molecular weight: 295.31g/mol
Use:
- 4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid can be used as an organic synthesis intermediate.
-It can be used to synthesize biologically active compounds, such as drugs, dyes and other organic family compounds.
Preparation Method: The preparation of
- 4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid is generally carried out by the following steps:
1. Add 2 '-N-Boc-pyrrole to benzoic acid under appropriate reaction conditions.
2. the reaction product is crystallized or purified to obtain 4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]benzoic acid.
Safety Information:
- 4-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl] The specific safety of benzoic acid also needs to be evaluated according to its use conditions and actual conditions.
-Always follow laboratory safety practices and use appropriate personal protective equipment (e. g., gloves, lab clothes, and goggles) during handling and storage.
-The compound may be irritating to the eyes, skin and respiratory tract, so be careful to avoid contact with these areas.
-In case of accidental exposure or inhalation, flush the affected area immediately with plenty of water and seek medical assistance.
Last Update：2024-04-09 20:49:11
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